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Mpp4tm1Wij
Targeted Allele Detail
Nomenclature
Symbol: Mpp4tm1Wij
Name: membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4); targeted mutation 1, Jan Wijnholds
MGI ID: MGI:3624689
Synonyms: Mpp4-
Gene: Mpp4  Location: Chr1:59120935-59163389 bp, - strand  Genetic Position: Chr1, 29.2 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:108232
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting construct containing a PGK-neo was inserted to replace intron 7 and 123 bp of exons 7 and 8, resulting in the generation of a frame shift in the 5' part of exon 7 encoding the PDZ domain of the protein. (J:108232)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mpp4 Mutation:  34 strains or lines available
References
Original:  J:108232 Aartsen WM, et al., Mpp4 recruits Psd95 and Veli3 towards the photoreceptor synapse. Hum Mol Genet. 2006 Apr 15;15(8):1291-302
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory