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Pawrtm1.1Yshi
Targeted Allele Detail
Nomenclature
Symbol: Pawrtm1.1Yshi
Name: PRKC, apoptosis, WT1, regulator; targeted mutation 1.1, Yang Shi
MGI ID: MGI:3624677
Synonyms: mpar-4
Gene: Pawr  Location: Chr10:108332121-108414240 bp, + strand  Genetic Position: Chr10, 56.43 cM, cytoband D1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:108228
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExons 4 and 5 were removed via cre mediated recombination. Western blot confirmed absence of protein in mutants. (J:108228)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pawr Mutation:  14 strains or lines available
References
Original:  J:108228 Affar el B, et al., Targeted ablation of Par-4 reveals a cell type-specific susceptibility to apoptosis-inducing agents. Cancer Res. 2006 Apr 1;66(7):3456-62
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory