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Targeted Allele Detail
Symbol: Palldtm1Zgwg
Name: palladin, cytoskeletal associated protein; targeted mutation 1, Zhugang Wang
MGI ID: MGI:3623949
Gene: Palld  Location: Chr8:61511433-61902690 bp, - strand  Genetic Position: Chr8, 31.23 cM, cytoband B3.3
Germline Transmission:  Earliest citation of germline transmission: J:100650
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA targeting construct was designed to replace exons 17 and 18 and part of 19, sequence encoding the three Ig-like domains, with a PGK-neo cassette. Western blot failed to detect either the main isoform. (J:100650)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Palld Mutation:  34 strains or lines available
Original:  J:100650 Luo H, et al., Disruption of palladin results in neural tube closure defects in mice. Mol Cell Neurosci. 2005 Aug;29(4):507-15
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory