About   Help   FAQ
Targeted Allele Detail
Symbol: Del(18Pcdhg)1Xzw
Name: deletion, Chr 18, Xiaozhong Wang 1
MGI ID: MGI:3623611
Synonyms: Del(18Pcdhga1-Pcdhgc3)1Jrs, Del1Jrs, Pcdh-gdel
Gene: Del(18Pcdhg)1Xzw  Location: unknown  Genetic Position: Chr18, Syntenic
Germline Transmission:  Earliest citation of germline transmission: J:107735
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutation:    Intergenic deletion
Mutation detailsCre mediated recombination resulted in the deletion of the protocadherin gamma locus extending from subfamily A, 1 to the third common exon. Northern blot using a probe for the protocadherin gamma common exons confirmed the complete loss of transcript in mutants. Absence of protein was confirmed by Western blot analysis. (J:107735)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(18Pcdhg)1Xzw Mutation:  0 strains or lines available
Original:  J:107735 Wang X, et al., Gamma protocadherins are required for survival of spinal interneurons. Neuron. 2002 Dec 5;36(5):843-54
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.14
The Jackson Laboratory