About   Help   FAQ
Gene trapped Allele Detail
Symbol: Pomgnt1Gt(OST179231)Lex
Name: protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase; gene trap OST179231, Lexicon Genetics
MGI ID: MGI:3623521
Synonyms: POMGnT1-, Pomgnt1Gt(Betageo-btk)1Lex
Gene: Pomgnt1  Location: Chr4:116123840-116159849 bp, + strand  Genetic Position: Chr4, 53.1 cM, cytoband C7
Mutant Cell Line:  OST179231 (Lexicon Genetics)
Germline Transmission:  Earliest citation of germline transmission: J:107697
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector
Mutation detailsA gene trap vector containing Betageo-btk was inserted into exon 2 of the locus in the 5' UTR, 35 nucleotides upstream of the start codon. Northern blot from mutant skeletal muscle confirmed absence of transcript. (J:107697)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pomgnt1 Mutation:  44 strains or lines available
Original:  J:107697 Liu J, et al., A genetic model for muscle-eye-brain disease in mice lacking protein O-mannose 1,2-N-acetylglucosaminyltransferase (POMGnT1). Mech Dev. 2006 Mar;123(3):228-40
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.03
The Jackson Laboratory