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Pomgnt1Gt(OST179231)Lex
Gene trapped Allele Detail
Nomenclature
Symbol: Pomgnt1Gt(OST179231)Lex
Name: protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase; gene trap OST179231, Lexicon Genetics
MGI ID: MGI:3623521
Synonyms: POMGnT1-, Pomgnt1Gt(Betageo-btk)1Lex
Gene: Pomgnt1  Location: Chr4:116150498-116159844 bp, + strand  Genetic Position: Chr4, 53.1 cM, cytoband C7
Mutation
origin
Mutant Cell Line:  OST179231
Germline Transmission:  Earliest citation of germline transmission: J:107697
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector
 
Mutation detailsA gene trap vector containing Betageo-btk was inserted into exon 2 of the locus in the 5' UTR, 35 nucleotides upstream of the start codon. Northern blot from mutant skeletal muscle confirmed absence of transcript. (J:107697)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 14 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pomgnt1 Mutation:  22 strains or lines available
References
Original:  J:107697 Liu J, et al., A genetic model for muscle-eye-brain disease in mice lacking protein O-mannose 1,2-N-acetylglucosaminyltransferase (POMGnT1). Mech Dev. 2006 Mar;123(3):228-40
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/22/2020
MGI 6.16
The Jackson Laboratory