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Angptl3tm1Kfuj
Targeted Allele Detail
Nomenclature
Symbol: Angptl3tm1Kfuj
Name: angiopoietin-like 3; targeted mutation 1, Kazunori Fujimoto
MGI ID: MGI:3623491
Gene: Angptl3  Location: Chr4:99030954-99046111 bp, + strand  Genetic Position: Chr4, 45.6 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:107479
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire locus except for part of exon 1 , was replaced with a neomycin resistance gene. Northern blot demonstrated that transcript was not detected in mutants. (J:107479)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Angptl3 Mutation:  16 strains or lines available
References
Original:  J:107479 Fujimoto K, et al., Angptl3-null mice show low plasma lipid concentrations by enhanced lipoprotein lipase activity. Exp Anim. 2006 Jan;55(1):27-34
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory