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Targeted Allele Detail
Symbol: Adipoqtm1Pesch
Name: adiponectin, C1Q and collagen domain containing; targeted mutation 1, Philipp E Scherer
MGI ID: MGI:3623488
Synonyms: Adipoqtm1Pesc
Gene: Adipoq  Location: Chr16:23146536-23157968 bp, + strand  Genetic Position: Chr16, 13.96 cM, cytoband B3-B4
Germline Transmission:  Earliest citation of germline transmission: J:107486
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA targeting vector was designed to replace exon 1, exon 2 and the coding part of exon 3 with a neomycin resistance gene. Western blot failed to detect protein in mutants. (J:107486)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adipoq Mutation:  29 strains or lines available
Original:  J:107486 Nawrocki AR, et al., Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists. J Biol Chem. 2006 Feb 3;281(5):2654-60
All:  24 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.15
The Jackson Laboratory