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Targeted Allele Detail
Symbol: Slc26a6tm1Psar
Name: solute carrier family 26, member 6; targeted mutation 1, Peter S Aronson
MGI ID: MGI:3623454
Synonyms: Slc26a6-
Gene: Slc26a6  Location: Chr9:108853283-108913049 bp, + strand  Genetic Position: Chr9, 59.63 cM, cytoband F2
Germline Transmission:  Earliest citation of germline transmission: J:107558
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA targeting vector was designed to disrupt the locus by replacing parts of exons 2 and 5 and all of exons 3 and 4 with a neomycin resistance cassette. Northern blot of mutant kidney confirmed absence of the major 2.7 kb transcript. Immunoblot confirmed absence of protein in mutants. (J:107558)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc26a6 Mutation:  23 strains or lines available
Original:  J:107558 Jiang Z, et al., Calcium oxalate urolithiasis in mice lacking anion transporter Slc26a6. Nat Genet. 2006 Apr;38(4):474-8
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory