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Targeted Allele Detail
Symbol: Avpr1atm1Gzt
Name: arginine vasopressin receptor 1A; targeted mutation 1, Gozoh Tsujimoto
MGI ID: MGI:3623418
Synonyms: V1a-, V1aR-, V1aR KO
Gene: Avpr1a  Location: Chr10:122448499-122453452 bp, + strand  Genetic Position: Chr10, 70.36 cM, cytoband D3
Germline Transmission:  Earliest citation of germline transmission: J:107607
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA targeting vector was designed to replace parts of the first exon and the first intron with a neomycin resistance cassette. RT-PCR failed to detect transcripts in any mutant tissues that were examined. (J:110099)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Avpr1a Mutation:  26 strains or lines available
Original:  J:107607 Egashira N, et al., V1a receptor knockout mice exhibit impairment of spatial memory in an eight-arm radial maze. Neurosci Lett. 2004 Feb 19;356(3):195-8
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory