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Afdntm1Ytk
Targeted Allele Detail
Nomenclature
Symbol: Afdntm1Ytk
Name: afadin, adherens junction formation factor; targeted mutation 1, Yoshimi Takai
MGI ID: MGI:3623108
Synonyms: afadin-
Gene: Afdn  Location: Chr17:13760391-13905798 bp, + strand  Genetic Position: Chr17, 8.95 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:57589
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin resistance gene replaced exon 2. (J:57589)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Afdn Mutation:  7 strains or lines available
References
Original:  J:57589 Ikeda W, et al., Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis. J Cell Biol. 1999 Sep 6;146(5):1117-32
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory