Tg(Tagln-rtTA-cre)1Llw
Transgene Detail

Summary

• Symbol: Tg(Tagln-rtTA-cre)1Llw
• Name: transgene insertion 1, Lucy Liaw
• MGI ID: MGI:3620643
• Synonyms: SM22alphartTACre
• Transgene: Tg(Tagln-rtTA-cre)1Llw Location: unknown
• Alliance: Tg(Tagln-rtTA-cre)1Llw page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase, Transactivator)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(Tagln-rtTA-cre)1Llw expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Tagln

• Mutation details: The transgelin promoter drives the expression of the rtTA transactivator in this transgene. When doxycycline is present, the transactivator binds to the tet responsive element (tetO) to direct cre expression. The reverse tetracycline-controlled transactivator was modified to be inducible by lower concentrations of doxycycline with greater control of basal expression. (J:106451)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tagln (species not specified) Summary of all recombinase alleles driven by Tagln. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:106451 Hara-Kaonga B, et al., Variable recombination efficiency in responder transgenes activated by cre recombinase in the vasculature. Transgenic Res. 2006 Feb;15(1):101-6
• All: 1 reference(s)