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Fgfr1tm5.2Sor
Targeted Allele Detail
Nomenclature
Symbol: Fgfr1tm5.2Sor
Name: fibroblast growth factor receptor 1; targeted mutation 5.2, Philippe Soriano
MGI ID: MGI:3620061
Synonyms: Fgfrdeltaex4
Gene: Fgfr1  Location: Chr8:25513654-25575714 bp, + strand  Genetic Position: Chr8, 14.12 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105920
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 4 was flanked by loxP sites via homologous recombination. Exon 4 is the first allele common to all splice variants. Cre-mediated excision of exon 4 was accomplished by breeding to a Cre-expressing line. (J:105920)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr1 Mutation:  171 strains or lines available
References
Original:  J:105920 Hoch RV, et al., Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 during mouse development. Development. 2006 Feb;133(4):663-73
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory