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Urostm2Cged
Targeted Allele Detail
Nomenclature
Symbol: Urostm2Cged
Name: uroporphyrinogen III synthase; targeted mutation 1, Cecile Ged
MGI ID: MGI:3620007
Synonyms: Urosdel
Gene: Uros  Location: Chr7:133686243-133710072 bp, - strand  Genetic Position: Chr7, 77.26 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:107043
Parent Cell Line:  H1 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance gene was inserted into the locus, replacing part of the coding sequence. The resulting transcript encodes a truncated protein of 204 amino acids instead of 265. (J:107043)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Uros Mutation:  14 strains or lines available
References
Original:  J:107043 Bensidhoum M, et al., The disruption of mouse uroporphyrinogen III synthase (uros) gene is fully lethal. Transgenics. 1998;2:275-280
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory