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Tbx1tm2.2Bem
Targeted Allele Detail
Nomenclature
Symbol: Tbx1tm2.2Bem
Name: T-box 1; targeted mutation 2.2, Bernice E Morrow
MGI ID: MGI:3619150
Synonyms: Tbx1-, Tbx1tm1.2Bem
Gene: Tbx1  Location: Chr16:18581713-18586969 bp, - strand  Genetic Position: Chr16, 11.51 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105980
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exons 2 and 3 were removed via cre-mediated excision. The ATG is in exon 2. (J:105980)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 7 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx1 Mutation:  11 strains or lines available
References
Original:  J:105980 Arnold JS, et al., Inactivation of Tbx1 in the pharyngeal endoderm results in 22q11DS malformations. Development. 2006 Mar;133(5):977-87
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory