About   Help   FAQ
Tbx1tm2.1Bem
Targeted Allele Detail
Nomenclature
Symbol: Tbx1tm2.1Bem
Name: T-box 1; targeted mutation 2.1, Bernice E Morrow
MGI ID: MGI:3619149
Synonyms: Tbx1flox, Tbx1tm1.1Bem
Gene: Tbx1  Location: Chr16:18581713-18586969 bp, - strand  Genetic Position: Chr16, 11.51 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105980
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exons 2 and 3 were flanked with loxP sites. The ATG is in exon 2. (J:105980)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx1 Mutation:  11 strains or lines available
References
Original:  J:105980 Arnold JS, et al., Inactivation of Tbx1 in the pharyngeal endoderm results in 22q11DS malformations. Development. 2006 Mar;133(5):977-87
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory