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Ccng1tm1Sst
Targeted Allele Detail
Nomenclature
Symbol: Ccng1tm1Sst
Name: cyclin G1; targeted mutation 1, Snorri S Thorgeirsson
MGI ID: MGI:3619024
Gene: Ccng1  Location: Chr11:40748552-40755311 bp, - strand  Genetic Position: Chr11, 24.42 cM, cytoband B1.1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:106007
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA PGK-neo resulted in the deletion of 1.3-kb consisting of 199 bp of exon 1, all of intron 1 and 168 bp of exon 2. The deleted sequence included the ATG and most of the cyclin box motif. Northern blot confirmed absence of transcript in mutant livers. (J:106007)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccng1 Mutation:  11 strains or lines available
References
Original:  J:106007 Jensen MR, et al., Reduced hepatic tumor incidence in cyclin G1-deficient mice. Hepatology. 2003 Apr;37(4):862-70
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory