About   Help   FAQ
Notch2tm3Grid
Targeted Allele Detail
Summary
Symbol: Notch2tm3Grid
Name: notch 2; targeted mutation 3, Tom Gridley
MGI ID: MGI:3617328
Synonyms: N2f, N2flox, Notch2f, Notch2Fl, Notch2flox
Gene: Notch2  Location: Chr3:97920854-98057683 bp, + strand  Genetic Position: Chr3, 42.42 cM
Alliance: Notch2tm3Grid page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105278
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    loxP sites were inserted to flank exon 3. (J:105278)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 106 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 24 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Notch2 Mutation:  97 strains or lines available
References
Original:  J:105278 McCright B, et al., Generation of new Notch2 mutant alleles. Genesis. 2006 Jan;44(1):29-33
All:  82 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory