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Targeted Allele Detail
Symbol: Gpr3tm1Cled
Name: G-protein coupled receptor 3; targeted mutation 1, Catherine Ledent
MGI ID: MGI:3615760
Synonyms: Gpr3-
Gene: Gpr3  Location: Chr4:133209340-133212536 bp, - strand  Genetic Position: Chr4, 66.24 cM, cytoband D3
Oocytes from superovulated Gpr3tm1Cled/Gpr3tm1Cled females display age-dependent increase in fragmentation

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:105182
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA targeting vector was designed to replace the entire coding sequence with a neomycin resistance cassette in reverse orientation. (J:105182)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpr3 Mutation:  5 strains or lines available
Original:  J:105182 Ledent C, et al., Premature ovarian aging in mice deficient for Gpr3. Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8922-6
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.03
The Jackson Laboratory