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Targeted Allele Detail
Symbol: Mapk12tm1Cnd
Name: mitogen-activated protein kinase 12; targeted mutation 1, Ana Cuenda
MGI ID: MGI:3615494
Synonyms: p38gamma-
Gene: Mapk12  Location: Chr15:89130584-89140703 bp, - strand  Genetic Position: Chr15, 44.65 cM
Germline Transmission:  Earliest citation of germline transmission: J:105203
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance gene was inserted to replace exon 3 by homologous recombination. Immunoblot failed to detect protein in mutants. (J:105203)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapk12 Mutation:  2 strains or lines available
Original:  J:105203 Sabio G, et al., p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP. EMBO J. 2005 Mar 23;24(6):1134-45
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory