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Muc2wnn
Chemically induced Allele Detail
Nomenclature
Symbol: Muc2wnn
Name: mucin 2; winnie
MGI ID: MGI:3614806
Gene: Muc2  Location: Chr7:141690340-141754693 bp, + strand  Genetic Position: Chr7, 87.1 cM, cytoband F5
Spontaneous colitis in Muc2wnn/Muc2wnn mice

Show the 7 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C57BL/6JSfdAnu
Project Collection: APF ENU Mutagenesis
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis mutation was identified in an ENU mutagenesis screen. It constitutes a G-to-A transition at genomic nucleotide position +9414 from the translation initiation site, which replaces cysteine with tyrosine at amino acid position 986 of the protein (C986Y).
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Muc2 Mutation:  5 strains or lines available
References
Original:  J:104190 The Australian Phenomics Facility at The Australian National University, Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University. MGI Direct Data Submission. 2006-2014;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory