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Polhtm1.1Rak
Targeted Allele Detail
Nomenclature
Symbol: Polhtm1.1Rak
Name: polymerase (DNA directed), eta (RAD 30 related); targeted mutation 1.1, Raju Kucherlapati
MGI ID: MGI:3614412
Synonyms: Pol eta-del4, XP-V
Gene: Polh  Location: Chr17:46172004-46202625 bp, - strand  Genetic Position: Chr17, 22.9 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105034
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Polh Mutation:  14 strains or lines available
References
Original:  J:105034 Lin Q, et al., Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice. Cancer Res. 2006 Jan 1;66(1):87-94
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory