Olig2^tm1Qrlu
Targeted Allele Detail

Summary

• Symbol: Olig2^tm1Qrlu
• Name: oligodendrocyte transcription factor 2; targeted mutation 1, Q Richard Lu
• MGI ID: MGI:3614399
• Gene: Olig2 Location: Chr16:91022345-91025565 bp, + strand Genetic Position: Chr16, 52.6 cM
• Alliance: Olig2^tm1Qrlu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:105071
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank the coding region, as well as an FRT-flanked neomycin selection cassette. (J:105071)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Olig2 Mutation: 46 strains or lines available

References

• Original: J:105071 Yue T, et al., A critical role for dorsal progenitors in cortical myelination. J Neurosci. 2006 Jan 25;26(4):1275-80
• All: 12 reference(s)