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Tg(MMTV-PyVT*Y315F*Y322F)Db-1Mul
Transgene Detail
Nomenclature
Symbol: Tg(MMTV-PyVT*Y315F*Y322F)Db-1Mul
Name: transgene insertion Db-1, William Muller
MGI ID: MGI:3614340
Synonyms: MMTV/MT-Y315/322F, MMTV-PyVmT Y315/322F, Tg(MMTV-PyVT*Y315F,Y322F)Db-1Mul
Transgene: Tg(MMTV-PyVT*Y315F*Y322F)Db-1Mul  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (random, expressed)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Total of 7 lines were produced, of which six lines Db-1, Db-3, Db-4, Db-5, Db-6 and Db-7 had similar phenotype. These mice were used to study metastatic disease and they had similar phenotype.

References
Original:  J:56327 Webster MA, et al., Requirement for both Shc and phosphatidylinositol 3' kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis. Mol Cell Biol. 1998 Apr;18(4):2344-59
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory