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Abi1tm1Pen
Targeted Allele Detail
Nomenclature
Symbol: Abi1tm1Pen
Name: abl-interactor 1; targeted mutation 1, Ann Marie Pendergast
MGI ID: MGI:3613611
Synonyms: abi1-
Gene: Abi1  Location: Chr2:22940073-23040241 bp, - strand  Genetic Position: Chr2, 15.18 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:104623
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast extracts. (J:169009)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abi1 Mutation:  72 strains or lines available
References
Original:  J:104623 Zipfel PA, et al., Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling. Curr Biol. 2006 Jan 10;16(1):35-46
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory