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Chrm5tm1Minm
Targeted Allele Detail
Nomenclature
Symbol: Chrm5tm1Minm
Name: cholinergic receptor, muscarinic 5; targeted mutation 1, Minoru Matsui
MGI ID: MGI:3613514
Synonyms: Chrm5-, M5 KO
Gene: Chrm5  Location: Chr2:112479171-112480769 bp, - strand  Genetic Position: Chr2, 57.02 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105126
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector containing a PGK-neo replaced most of the coding sequence. RT-PCR failed to detect transcript in mutant brains. (J:105126)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Chrm5 Mutation:  19 strains or lines available
References
Original:  J:105126 Nakamura T, et al., M(3) muscarinic acetylcholine receptor plays a critical role in parasympathetic control of salivation in mice. J Physiol. 2004 Jul 15;558(Pt 2):561-75
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory