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Targeted Allele Detail
Symbol: Mobptm1Irg
Name: myelin-associated oligodendrocytic basic protein; targeted mutation 1, I R Griffiths
MGI ID: MGI:3613469
Synonyms: Mobp-
Gene: Mobp  Location: Chr9:120149742-120181484 bp, + strand  Genetic Position: Chr9, 71.41 cM
Germline Transmission:  Earliest citation of germline transmission: J:104861
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S1/SvImJ
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA targeting construct was designed to replace exons 3-5, including coding sequence for the first 68 amino acid residues common to all known isoforms and all potential transcription start sites. Western blot analysis failed to detect protein from mutant mice. (J:104861)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mobp Mutation:  18 strains or lines available
Original:  J:104861 Yool D, et al., Phenotypic analysis of mice deficient in the major myelin protein MOBP, and evidence for a novel Mobp isoform. Glia. 2002 Sep;39(3):256-67
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
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