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Targeted Allele Detail
Symbol: Cntn6tm1Kwat
Name: contactin 6; targeted mutation 1, Kazutada Watanabe
MGI ID: MGI:3613462
Synonyms: NB-3-
Gene: Cntn6  Location: Chr6:104492790-104863406 bp, + strand  Genetic Position: Chr6, 48.93 cM, cytoband E2
Germline Transmission:  Earliest citation of germline transmission: J:104862
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe genomic region encoding the secretion signal and part of the first Ig-domain were replaced with a lacZ and neo cassette. LacZ expression was detected in the accessory olfactory bulb, anterodorsal thalamic nuclei, inferior colliculi, layer 5 of the cerebral cortex and the cerebellum. Western blot failed to detect protein in mutant brains. (J:61081, J:104862)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cntn6 Mutation:  45 strains or lines available
Original:  J:104862 Takeda Y, et al., Impaired motor coordination in mice lacking neural recognition molecule NB-3 of the contactin/F3 subgroup. J Neurobiol. 2003 Sep 5;56(3):252-65
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory