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Artm4(AR)Dmr
Targeted Allele Detail
Nomenclature
Symbol: Artm4(AR)Dmr
Name: androgen receptor; targeted mutation 1, Andrew P Lieberman
MGI ID: MGI:3612537
Synonyms: AR113Q, Artm1Apl
Gene: Ar  Location: ChrX:98149721-98323215 bp, + strand  Genetic Position: ChrX, 42.82 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:104360
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
    Part of exon 1 was replaced by human AR exon 1 sequence with 113 CAG repeats. (J:104360)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ar Mutation:  20 strains or lines available
References
Original:  J:104360 Yu Z, et al., Abnormalities of Germ Cell Maturation and Sertoli Cell Cytoskeleton in Androgen Receptor 113 CAG Knock-In Mice Reveal Toxic Effects of the Mutant Protein. Am J Pathol. 2006 Jan;168(1):195-204
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory