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Targeted Allele Detail
Symbol: Lama1tm1.1Olf
Name: laminin, alpha 1; targeted mutation 1.1, Olivier Lefebvre
MGI ID: MGI:3611213
Synonyms: Lama1delta
Gene: Lama1  Location: Chr17:67697265-67822645 bp, + strand  Genetic Position: Chr17, 38.8 cM
Lama1nmf223/Lama1tm1.1Olf mice experience vitreal fibroplasia and vessel tortuosity

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:102740
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S2/SvPas
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThe loxP-flanked region encompassing part of the promoter region, the transcription start site, and the first exon was excised in the germline. (J:102740)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lama1 Mutation:  97 strains or lines available
Original:  J:102740 Alpy F, et al., Generation of a conditionally null allele of the laminin alpha1 gene. Genesis. 2005 Oct;43(2):59-70
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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