Lama1^tm1.1Olf
Targeted Allele Detail

Nomenclature

Symbol:	Lama1^tm1.1Olf
Name:	laminin, alpha 1; targeted mutation 1.1, Olivier Lefebvre
MGI ID:	MGI:3611213
Synonyms:	Lama1^delta
Gene:	Lama1  Location: Chr17:67697265-67822645 bp, + strand  Genetic Position: Chr17, 38.8 cM

Lama1^nmf223/Lama1^tm1.1Olf mice experience vitreal fibroplasia and vessel tortuosity

Show the 1 phenotype image(s) involving this allele.

Mutation origin

Germline Transmission:	Earliest citation of germline transmission: J:102740
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S2/SvPas

Mutation description

Allele Type:		Targeted (Null/knockout)
Mutation:		Intragenic deletion
		Mutation details: The loxP-flanked region encompassing part of the promoter region, the transcription start site, and the first exon was excised in the germline. (J:102740)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lama1 Mutation:	9 strains or lines available

References

Original:	J:102740 Alpy F, et al., Generation of a conditionally null allele of the laminin alpha1 gene. Genesis. 2005 Oct;43(2):59-70
All:	4 reference(s)