About   Help   FAQ
Targeted Allele Detail
Symbol: Loxtm1Soin
Name: lysyl oxidase; targeted mutation 1, Raija Soininen
MGI ID: MGI:3610732
Synonyms: Lox-
Gene: Lox  Location: Chr18:52516069-52529867 bp, - strand  Genetic Position: Chr18, 28.22 cM
Germline Transmission:  Earliest citation of germline transmission: J:103389
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsCre mediated recombination was used to excise exon 1, from about 600 bp upstream of the translation start codon to about 90 bp downstream of exon 1. Northern blot confirmed complete inactivation of the gene. (J:103389)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lox Mutation:  11 strains or lines available
Original:  J:103389 Maki JM, et al., Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice. Circulation. 2002 Nov 5;106(19):2503-9
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.11
The Jackson Laboratory