Irx5^tm1Hui
Targeted Allele Detail

Summary

• Symbol: Irx5^tm1Hui
• Name: Iroquois homeobox 5; targeted mutation 1, Chi-chung Hui
• MGI ID: MGI:3610374
• Synonyms: Irx5^-
• Gene: Irx5 Location: Chr8:93084424-93088084 bp, + strand Genetic Position: Chr8, 44.93 cM
• Alliance: Irx5^tm1Hui page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103461
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Part of exon 1 was replaced with a PGK-neo cassette. (J:103461)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Irx5 Mutation: 30 strains or lines available

References

• Original: J:103461 Cheng CW, et al., The Iroquois homeobox gene, Irx5, is required for retinal cone bipolar cell development. Dev Biol. 2005 Nov 1;287(1):48-60
• All: 5 reference(s)