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Tg(F2RL1)1Mslb
Transgene Detail
Nomenclature
Symbol: Tg(F2RL1)1Mslb
Name: transgene insertion 1, Mary Stevens
MGI ID: MGI:3609028
Synonyms: PAR2tg, Tg(F2RL1)1Nwb
Transgene: Tg(F2RL1)1Mslb  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/NCrl
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(F2RL1)1Mslb expresses 1 gene
 
Mutation detailsThe transgene comprises the entire human gene, including the promoter and at least 30 kb of flanking genomic DNA, from the BAC clone 23C20. The number of integrated copies, based on Southern blot analysis, is between between 5 and 10 per diploid genome. Northern blot analysis revealed high levels of transgene-derived mRNA in liver, skin, and spleen and lower levels in lung, heart and testis. (J:79757)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:79757 Schmidlin F, et al., Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway. J Immunol. 2002 Nov 1;169(9):5315-21
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory