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Targeted Allele Detail
Symbol: Epb41l3tm1Jkis
Name: erythrocyte membrane protein band 4.1 like 3; targeted mutation 1, Joseph L Kissil
MGI ID: MGI:3609004
Synonyms: 4.1B-
Gene: Epb41l3  Location: Chr17:69156810-69289985 bp, + strand  Genetic Position: Chr17, 40.15 cM
Germline Transmission:  Earliest citation of germline transmission: J:102380
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance cassette replaced most of the 3' sequence in exon 3, which is the second coding exon of the 4.1B locus and contains the initiating codon of the Dal-1 isoform. Western blot failed to detect protein in mutant mice. (J:102380)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Epb41l3 Mutation:  4 strains or lines available
Original:  J:102380 Yi C, et al., Loss of the putative tumor suppressor band 4.1B/Dal1 gene is dispensable for normal development and does not predispose to cancer. Mol Cell Biol. 2005 Nov;25(22):10052-9
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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