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Tg(Tek-cre)1Rwng
Transgene Detail
Nomenclature
Symbol: Tg(Tek-cre)1Rwng
Name: transgene insertion 1, Rong Wang
MGI ID: MGI:3608912
Synonyms: Tg(Tek-cre)1Lfr, tie2-cre, Tie2Cre
Transgene: Tg(Tek-cre)1Rwng  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe endothelial specific receptor tyrosine kinase promoter was used to drive expression of cre recombinase. Nine founder lines were produced and one of these was selected for use that efficiently mediated gene excision. Cre was active in the blood islands of extraembryonic mesoderm at E7.5 and in the dorsal aortae at E8.5. By E11.5 it was active in the endothelial cells of all blood vessels. (J:102190, J:104401)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tek     Summary of all recombinase alleles driven by Tek.
 

Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:102190 Proctor JM, et al., Vascular development of the brain requires beta8 integrin expression in the neuroepithelium. J Neurosci. 2005 Oct 26;25(43):9940-8
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory