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P2rx7tm1Ipch
Targeted Allele Detail
Nomenclature
Symbol: P2rx7tm1Ipch
Name: purinergic receptor P2X, ligand-gated ion channel, 7; targeted mutation 1, Iain P Chessell
MGI ID: MGI:3606250
Synonyms: Glaxo P2X7R-, P2X7-, P2X7R-
Gene: P2rx7  Location: Chr5:122643911-122691432 bp, + strand  Genetic Position: Chr5, 62.5 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101945
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Exon 1 of the locus was disrupted by insertion of a lacZ sequence. (J:101945)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any P2rx7 Mutation:  15 strains or lines available
References
Original:  J:101945 Chessell IP, et al., Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain. Pain. 2005 Apr;114(3):386-96
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory