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Foxs1tm1Sven
Targeted Allele Detail
Summary
Symbol: Foxs1tm1Sven
Name: forkhead box S1; targeted mutation 1, Sven Enerback
MGI ID: MGI:3606198
Synonyms: Foxs1Beta-gal
Gene: Foxs1  Location: Chr2:152773818-152775128 bp, - strand  Genetic Position: Chr2, 75.41 cM, cytoband H2
Alliance: Foxs1tm1Sven page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99183
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsAn NLS-lacZ cassette was inserted after the first 16 amino acids of the locus, replacing the DNA binding region. Staining indicated that expression of lacZ reflected expression of endogenous protein. (J:99183)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxs1 Mutation:  23 strains or lines available
References
Original:  J:99183 Heglind M, et al., Lack of the central nervous system- and neural crest-expressed forkhead gene foxs1 affects motor function and body weight. Mol Cell Biol. 2005 Jul;25(13):5616-25
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory