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Efna3tm1Rax
Targeted Allele Detail
Nomenclature
Symbol: Efna3tm1Rax
Name: ephrin A3; targeted mutation 1, Richard Axel
MGI ID: MGI:3605006
Gene: Efna3  Location: Chr3:89313899-89322965 bp, - strand  Genetic Position: Chr3, 39.06 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101720
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2-4 were replaced with a neomycin resistance cassette. The splicing of exon 1 to 5 would result in a frameshift encoding a protein truncated after 45 amino acids, lacking 90% of the ectodomain. (J:101720)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Efna3 Mutation:  3 strains or lines available
References
Original:  J:101720 Cutforth T, et al., Axonal ephrin-As and odorant receptors: coordinate determination of the olfactory sensory map. Cell. 2003 Aug 8;114(3):311-22
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory