About   Help   FAQ
Itpr3tm1Kmik
Targeted Allele Detail
Nomenclature
Symbol: Itpr3tm1Kmik
Name: inositol 1,4,5-triphosphate receptor 3; targeted mutation 1, Katsuhiko Mikoshiba
MGI ID: MGI:3604625
Synonyms: IP3R3-, IP3R3KO, IP3R3 KO
Gene: Itpr3  Location: Chr17:27057304-27122223 bp, + strand  Genetic Position: Chr17, 13.68 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101380
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe first coding exon was disrupted downstream of the ATG by replacement of sequence with a neomycin resistance gene. Immunoblot confirmed absence of protein in mutants. (J:101380)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Itpr3 Mutation:  103 strains or lines available
References
Original:  J:101380 Futatsugi A, et al., IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism. Science. 2005 Sep 30;309(5744):2232-4
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/05/2017
MGI 6.11
The Jackson Laboratory