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Targeted Allele Detail
Symbol: Itpr3tm1Kmik
Name: inositol 1,4,5-triphosphate receptor 3; targeted mutation 1, Katsuhiko Mikoshiba
MGI ID: MGI:3604625
Synonyms: IP3R3-, IP3R3KO, IP3R3 KO
Gene: Itpr3  Location: Chr17:27057304-27122223 bp, + strand  Genetic Position: Chr17, 13.68 cM
Germline Transmission:  Earliest citation of germline transmission: J:101380
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe first coding exon was disrupted downstream of the ATG by replacement of sequence with a neomycin resistance gene. Immunoblot confirmed absence of protein in mutants. (J:101380)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Itpr3 Mutation:  43 strains or lines available
Original:  J:101380 Futatsugi A, et al., IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism. Science. 2005 Sep 30;309(5744):2232-4
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory