Gsk3b^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Gsk3b^tm1Dgen
• Name: glycogen synthase kinase 3 beta; targeted mutation 1, Deltagen
• MGI ID: MGI:3604596
• Synonyms: GSK-3beta^L
• Gene: Gsk3b Location: Chr16:37909363-38066446 bp, + strand Genetic Position: Chr16, 26.54 cM, cytoband B4
• Alliance: Gsk3b^tm1Dgen page

Mutation origin

• Mutant Cell Line: 7945
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in pituitary gland, brain, most other tissues examined except white fat; beta-galactosidase expression is detectable in all tissues examined.

Expression

In Mice Carrying this Mutation:

145 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gsk3b Mutation: 111 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 6 reference(s)