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Targeted Allele Detail
Symbol: Ptch2tm1Dgen
Name: patched 2; targeted mutation 1, Deltagen
MGI ID: MGI:3604587
Gene: Ptch2  Location: Chr4:116953272-116973298 bp, + strand  Genetic Position: Chr4, 53.41 cM, cytoband C-D
Alliance: Ptch2tm1Dgen page
Mutant Cell Line:  5341
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis on samples from heterozygous mice detects a gene transcript at high levels in testis and at lower levels in skin, urinary bladder, pituitary gland, adrenal gland, epididymis, coagulating gland, white fat, and most othe tissues examined; beta-galactosidase expression is detectable in brain, spinal cord, sciatic nerve, aorta, heart, lung, liver, pancreas, kidney, urinary bladder, thyroid gland, trachea, pituitary gland, adrenal glands, skeletal muscle, skin, testis, prostate gland, ovary, uterus and cervix.
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 58 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptch2 Mutation:  29 strains or lines available
See also, data as provided by Deltagen, Inc.
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory