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Targeted Allele Detail
Symbol: Scn9atm1Dgen
Name: sodium channel, voltage-gated, type IX, alpha; targeted mutation 1, Deltagen
MGI ID: MGI:3604573
Synonyms: Scn9atm10gen
Gene: Scn9a  Location: Chr2:66480080-66634962 bp, - strand  Genetic Position: Chr2, 39.13 cM
Mutant Cell Line:  4129
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects a gene transcript in many of the tissues analyzed except for lung, liver, kidney, bone marrow, and uterus, beta-galactosidase expression from this allele is detectable in brain, urinary bladder, trachea, larynx, pharynx, tongue, male reproductive system and neuronal ganglia.
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 56 assay results
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Scn9a Mutation:  66 strains or lines available
See also, data as provided by Deltagen, Inc.
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory