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Slc22a6tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Slc22a6tm1Dgen
Name: solute carrier family 22 (organic anion transporter), member 6; targeted mutation 1, Deltagen
MGI ID: MGI:3604571
Synonyms: Oat1-
Gene: Slc22a6  Location: Chr19:8617996-8628299 bp, + strand  Genetic Position: Chr19, 5.44 cM
Mutation
origin
Mutant Cell Line:  3797
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA bacterial lacZ gene and neomycin resistance cassette was inserted to replace a 52 bp segment within the coding portion of exon 1 such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects high levels of RNA transcripts in the kidney and very low levels in the brain, beta-galactosidase expression from this allele is detectable in brain and kidney. (J:108655)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 60 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc22a6 Mutation:  13 strains or lines available
Notes
See also, data as provided by Deltagen, Inc.
References
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory