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Targeted Allele Detail
Symbol: Sstr1tm1Dgen
Name: somatostatin receptor 1; targeted mutation 1, Deltagen
MGI ID: MGI:3604559
Gene: Sstr1  Location: Chr12:58258558-58261230 bp, + strand  Genetic Position: Chr12, 25.61 cM
Mutant Cell Line:  4113
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects high levels of gene transcript in pituitary gland and large intestine and lower levels in brain, cortex, subcortical region, cerebellum, brainstem, olfactory bulb, spinal cord, eye, Harderian gland, lung, spleen, lymph nodes, skin, gallbladder, urinary bladder, adrenal gland, stomach, small intestine, cecum, epididymis, prostate gland, ovaries, uterus and white fat, beta-galactosidase expression from this allele is detectable in brain, trachea, larynx, pituitary gland, tongue, and the male reproductive system.
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 67 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sstr1 Mutation:  14 strains or lines available
See also, data as provided by Deltagen, Inc.
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.19
The Jackson Laboratory