About   Help   FAQ
Thbs4tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Thbs4tm1Dgen
Name: thrombospondin 4; targeted mutation 1, Deltagen
MGI ID: MGI:3604558
Gene: Thbs4  Location: Chr13:92751590-92794818 bp, - strand  Genetic Position: Chr13, 47.75 cM
Mutation
origin
Mutant Cell Line:  6372
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects a gene transcript in most tissues analyzed, highest levels are seen in skin, gallbladder, skeletal muscle, tongue and ovary and no transcripts are detectable in bone marrow and cecum. Beta-galactosidase expression from this allele is detectable in brain, sciatic nerve, eyes, heart, larynx, skeletal muscle, testis and connective tissue.
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 39 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Thbs4 Mutation:  38 strains or lines available
Notes
See also, data as provided by Deltagen, Inc.
References
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/05/2017
MGI 6.11
The Jackson Laboratory