Thbs4^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Thbs4^tm1Dgen
• Name: thrombospondin 4; targeted mutation 1, Deltagen
• MGI ID: MGI:3604558
• Synonyms: TSP4 KO
• Gene: Thbs4 Location: Chr13:92888098-92931326 bp, - strand Genetic Position: Chr13, 47.75 cM
• Alliance: Thbs4^tm1Dgen page

Mutation origin

• Mutant Cell Line: 6372
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects a gene transcript in most tissues analyzed, highest levels are seen in skin, gallbladder, skeletal muscle, tongue and ovary and no transcripts are detectable in bone marrow and cecum. Beta-galactosidase expression from this allele is detectable in brain, sciatic nerve, eyes, heart, larynx, skeletal muscle, testis and connective tissue.

Expression

In Mice Carrying this Mutation:	39 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Thbs4 Mutation: 68 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 21 reference(s)