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Esrratm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Esrratm1Dgen
Name: estrogen related receptor, alpha; targeted mutation 1, Deltagen
MGI ID: MGI:3604552
Gene: Esrra  Location: Chr19:6910977-6921813 bp, - strand  Genetic Position: Chr19, 5.08 cM
Mutation
origin
Mutant Cell Line:  8363
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects a low level of gene transcript in cerebellum, heart, thymus, skin, gallbladder, pituitary gland, skeletal muscle, tongue and stomach, beta-galactosidase expression from this allele is detectable in most organs examined. Most striking expression was detected in the central nervous system, heart and kidney.
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 92 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Esrra Mutation:  13 strains or lines available
Notes
See also, data as provided by Deltagen, Inc.
References
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory