About   Help   FAQ
Adipor1tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Adipor1tm1Dgen
Name: adiponectin receptor 1; targeted mutation 1, Deltagen
MGI ID: MGI:3604517
Gene: Adipor1  Location: Chr1:134415378-134433351 bp, + strand  Genetic Position: Chr1, 58.22 cM, cytoband E4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122027
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are detectable in liver, gallbladder, urinary bladder, pituitary gland, adrenal gland, testis, coagulating gland, prostate gland, ovary, whole brain, cortex, subcortical region, cerebellum, brainstem, olfactory bulb, spinal cord, eye, Harderian glands, heart, lung, pancreas, kidney, spleen, thymus, lymph nodes, bone marrow, skin, salivary gland, skeletal muscle, tongue, stomach, small intestine, cecum, colon, epididymis, seminal vesicle, uterus and white fat. LacZ expression was detected in testis with moderate staining observed in some spermatogenic cells of the seminiferous tubules. (J:122027)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 52 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adipor1 Mutation:  32 strains or lines available
Notes
See also, data as provided by Deltagen, Inc.
References
Original:  J:122027 Bjursell M, et al., Opposing effects of adiponectin receptors 1 and 2 on energy metabolism. Diabetes. 2007 Mar;56(3):583-93
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/19/2017
MGI 6.10
The Jackson Laboratory