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Targeted Allele Detail
Symbol: Chst3tm1Dgen
Name: carbohydrate (chondroitin 6/keratan) sulfotransferase 3; targeted mutation 1, Deltagen
MGI ID: MGI:3604509
Synonyms: C6ST-1 KO
Gene: Chst3  Location: Chr10:60181534-60194239 bp, - strand  Genetic Position: Chr10, 29.7 cM, cytoband C
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are normally detectable in spleen and lymph nodes, spinal cord, eye, lung, pancreas, adrenal gland, stomach, testis, ovary, whole brain, cortex, subcortical region, cerebellum, brainstem, olfactory bulb, Harderian glands, heart, liver, kidney, thymus, bone marrow, skin, gallbladder, urinary bladder, pituitary gland, salivary gland, skeletal muscle, tongue, small intestine, cecum, colon, epididymis, seminal vesicle, coagulating gland, prostate gland, uterus and white fat. Strong lacZ expression was detected in most organs examined. LacZ expression was not detected in gallbladder and uterus.
View phenotypes for all genotypes (concatenated display).
Disease models
In Mice Carrying this Mutation: 96 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Chst3 Mutation:  10 strains or lines available
See also, data as provided by Deltagen, Inc.

Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.0
The Jackson Laboratory