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Targeted Allele Detail
Symbol: Trpm5tm1Dgen
Name: transient receptor potential cation channel, subfamily M, member 5; targeted mutation 1, Deltagen
MGI ID: MGI:3604455
Gene: Trpm5  Location: Chr7:142625266-142648379 bp, - strand  Genetic Position: Chr7, 88.11 cM
Alliance: Trpm5tm1Dgen page
Mutant Cell Line:  7921
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects highest levels of gene transcript in gallbladder and lower levels in thymus, tongue, stomach, small intestine, large intestine and cecum, beta-galactosidase expression from this allele is detectable in thymus, trachea, and testis.
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 35 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trpm5 Mutation:  37 strains or lines available
See also, data as provided by Deltagen, Inc.
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory