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Uchl1tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Uchl1tm1Dgen
Name: ubiquitin carboxy-terminal hydrolase L1; targeted mutation 1, Deltagen
MGI ID: MGI:3604452
Gene: Uchl1  Location: Chr5:66676091-66687234 bp, + strand  Genetic Position: Chr5, 35.95 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 6 through 8 and the first 6 bases of exon 9 were replaced by a lacZ-neomycin cassette. RT-PCR analysis detected a gene transcript in most tissues analyzed except for Harderian glands, liver, lymph nodes, bone marrow and skeletal muscle. Beta-galactosidase expression from this allele was detectable in brain, spinal cord, eyes, heart, pancreas, kidney, urinary bladder, pituitary gland, adrenal glands, testis, prostate gland, ovary and cervix. Western blot analysis of brain and spinal cord homogenates failed to detect any protein product. (J:156538)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 56 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Uchl1 Mutation:  19 strains or lines available
Notes
See also, data as provided by Deltagen, Inc.
References
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory